Methamphetamine alters microglial immune function through P2X7R signaling

BACKGROUND: Purinoceptors have emerged as mediators of chronic inflammation and neurodegenerative processes. The ionotropic purinoceptor P2X7 (P2X7R) is known to modulate proinflammatory signaling and integrate neuronal-glial circuits. Evidence of P2X7R involvement in neurodegeneration, chronic pain...

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Detalles Bibliográficos
Autores principales: Fernandes, Nicole C., Sriram, Uma, Gofman, Larisa, Cenna, Jonathan M., Ramirez, Servio H., Potula, Raghava
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847215/
https://www.ncbi.nlm.nih.gov/pubmed/27117066
http://dx.doi.org/10.1186/s12974-016-0553-3

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