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Infectious SIV resides in adipose tissue and induces metabolic defects in chronically infected rhesus macaques
BACKGROUND: HIV reservoirs pose major challenges to viral eradication. The main cellular reservoirs include CD4 T cells and macrophages, whereas anatomic reservoirs are thought to be primarily lymphoid tissues. Adipose tissue represents a potentially important non-lymphoid location for HIV replicati...
Autores principales: | Couturier, Jacob, Agarwal, Neeti, Nehete, Pramod N., Baze, Wallace B., Barry, Michael A., Jagannadha Sastry, K., Balasubramanyam, Ashok, Lewis, Dorothy E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847269/ https://www.ncbi.nlm.nih.gov/pubmed/27117277 http://dx.doi.org/10.1186/s12977-016-0260-2 |
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