Cargando…

Fibrin network pattern changes of platelet-rich fibrin in young versus old age group of individuals: A cell block cytology study

BACKGROUND: To evaluate variations in fibrin network patterns of the platelet-rich fibrin (PRF) in different age groups. MATERIALS AND METHODS: Ninety-five patients were divided into three age groups: Group 1: (20–39 years); Group 2: (40–59 years); and Group 3: (60 years and above). PRF was prepared...

Descripción completa

Detalles Bibliográficos
Autores principales: Yajamanya, Shravanthi Raghav, Chatterjee, Anirban, Babu, Chaitanya Nischay, Karunanithi, Deepika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847460/
https://www.ncbi.nlm.nih.gov/pubmed/27143826
http://dx.doi.org/10.4103/0972-124X.176390
_version_ 1782429219902455808
author Yajamanya, Shravanthi Raghav
Chatterjee, Anirban
Babu, Chaitanya Nischay
Karunanithi, Deepika
author_facet Yajamanya, Shravanthi Raghav
Chatterjee, Anirban
Babu, Chaitanya Nischay
Karunanithi, Deepika
author_sort Yajamanya, Shravanthi Raghav
collection PubMed
description BACKGROUND: To evaluate variations in fibrin network patterns of the platelet-rich fibrin (PRF) in different age groups. MATERIALS AND METHODS: Ninety-five patients were divided into three age groups: Group 1: (20–39 years); Group 2: (40–59 years); and Group 3: (60 years and above). PRF was prepared from blood samples of all patients and were subjected to cell block cytology method of histological analysis and slides were prepared to histologically assess the age-related changes in (i) fibrin network patterns in terms of density and (ii) entrapment of platelets and white blood cells (WBCs) within fibrin meshwork. RESULTS: Two types of fibrin network pattern arrangements noticed: Dense and loose types in three age groups. However, there was a noticeable decrease in the dense type of fibrin network with progressing age and increase in the loose type of fibrin arrangement. Furthermore, variation in a number of platelets and WBCs entrapped within fibrin network in relation to age was noticed. CONCLUSION: From the current study it can be concluded that age can be considered as one of the influencing factors on quality of PRF in terms of fibrin network patterns and hence, platelet and WBCs entrapment within these fibrin networks.
format Online
Article
Text
id pubmed-4847460
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-48474602016-05-03 Fibrin network pattern changes of platelet-rich fibrin in young versus old age group of individuals: A cell block cytology study Yajamanya, Shravanthi Raghav Chatterjee, Anirban Babu, Chaitanya Nischay Karunanithi, Deepika J Indian Soc Periodontol Original Article BACKGROUND: To evaluate variations in fibrin network patterns of the platelet-rich fibrin (PRF) in different age groups. MATERIALS AND METHODS: Ninety-five patients were divided into three age groups: Group 1: (20–39 years); Group 2: (40–59 years); and Group 3: (60 years and above). PRF was prepared from blood samples of all patients and were subjected to cell block cytology method of histological analysis and slides were prepared to histologically assess the age-related changes in (i) fibrin network patterns in terms of density and (ii) entrapment of platelets and white blood cells (WBCs) within fibrin meshwork. RESULTS: Two types of fibrin network pattern arrangements noticed: Dense and loose types in three age groups. However, there was a noticeable decrease in the dense type of fibrin network with progressing age and increase in the loose type of fibrin arrangement. Furthermore, variation in a number of platelets and WBCs entrapped within fibrin network in relation to age was noticed. CONCLUSION: From the current study it can be concluded that age can be considered as one of the influencing factors on quality of PRF in terms of fibrin network patterns and hence, platelet and WBCs entrapment within these fibrin networks. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC4847460/ /pubmed/27143826 http://dx.doi.org/10.4103/0972-124X.176390 Text en Copyright: © Journal of Indian Society of Periodontology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution NonCommercial ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Yajamanya, Shravanthi Raghav
Chatterjee, Anirban
Babu, Chaitanya Nischay
Karunanithi, Deepika
Fibrin network pattern changes of platelet-rich fibrin in young versus old age group of individuals: A cell block cytology study
title Fibrin network pattern changes of platelet-rich fibrin in young versus old age group of individuals: A cell block cytology study
title_full Fibrin network pattern changes of platelet-rich fibrin in young versus old age group of individuals: A cell block cytology study
title_fullStr Fibrin network pattern changes of platelet-rich fibrin in young versus old age group of individuals: A cell block cytology study
title_full_unstemmed Fibrin network pattern changes of platelet-rich fibrin in young versus old age group of individuals: A cell block cytology study
title_short Fibrin network pattern changes of platelet-rich fibrin in young versus old age group of individuals: A cell block cytology study
title_sort fibrin network pattern changes of platelet-rich fibrin in young versus old age group of individuals: a cell block cytology study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847460/
https://www.ncbi.nlm.nih.gov/pubmed/27143826
http://dx.doi.org/10.4103/0972-124X.176390
work_keys_str_mv AT yajamanyashravanthiraghav fibrinnetworkpatternchangesofplateletrichfibrininyoungversusoldagegroupofindividualsacellblockcytologystudy
AT chatterjeeanirban fibrinnetworkpatternchangesofplateletrichfibrininyoungversusoldagegroupofindividualsacellblockcytologystudy
AT babuchaitanyanischay fibrinnetworkpatternchangesofplateletrichfibrininyoungversusoldagegroupofindividualsacellblockcytologystudy
AT karunanithideepika fibrinnetworkpatternchangesofplateletrichfibrininyoungversusoldagegroupofindividualsacellblockcytologystudy