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Determination of the potency of a novel saw palmetto supercritical CO(2) extract (SPSE) for 5α-reductase isoform II inhibition using a cell-free in vitro test system

BACKGROUND: The nicotinamide adenine dinucleotide phosphate-dependent membrane protein 5α-reductase catalyses the conversion of testosterone to the most potent androgen – 5α-dihydrotestosterone. Two 5α-reductase isoenzymes are expressed in humans: type I and type II. The latter is found primarily in...

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Detalles Bibliográficos
Autores principales: Pais, Pilar, Villar, Agustí, Rull, Santiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847595/
https://www.ncbi.nlm.nih.gov/pubmed/27186566
http://dx.doi.org/10.2147/RRU.S96576