Endoplasmic reticulum stress induced by tunicamycin increases resistin messenger ribonucleic acid through the pancreatic endoplasmic reticulum eukaryotic initiation factor 2α kinase–activating transcription factor 4–CAAT/enhancer binding protein‐α homologous protein pathway in THP‐1 human monocytes

AIMS/INTRODUCTION: Resistin, secreted from adipocytes, causes insulin resistance in mice. In humans, the resistin gene is mainly expressed in monocytes and macrophages. Tunicamycin is known to induce endoplasmic reticulum (ER) stress, and reduce resistin gene expression in 3T3‐L1 mouse adipocytes. T...

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Detalles Bibliográficos
Autores principales: Hamada, Junpei, Onuma, Hiroshi, Ochi, Fumihiro, Hirai, Hiroki, Takemoto, Koji, Miyoshi, Akiko, Matsushita, Manami, Kadota, Yuko, Ohashi, Jun, Kawamura, Ryoichi, Takata, Yasunori, Nishida, Wataru, Hashida, Seiichi, Ishii, Eiichi, Osawa, Haruhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847884/
https://www.ncbi.nlm.nih.gov/pubmed/27330716
http://dx.doi.org/10.1111/jdi.12434

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