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Hypoxia-induced metabolic stress in retinal pigment epithelial cells is sufficient to induce photoreceptor degeneration

Photoreceptors are the most numerous and metabolically demanding cells in the retina. Their primary nutrient source is the choriocapillaris, and both the choriocapillaris and photoreceptors require trophic and functional support from retinal pigment epithelium (RPE) cells. Defects in RPE, photorecep...

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Detalles Bibliográficos
Autores principales:	Kurihara, Toshihide, Westenskow, Peter D, Gantner, Marin L, Usui, Yoshihiko, Schultz, Andrew, Bravo, Stephen, Aguilar, Edith, Wittgrove, Carli, Friedlander, Mollie SH, Paris, Liliana P, Chew, Emily, Siuzdak, Gary, Friedlander, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2016
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848091/ https://www.ncbi.nlm.nih.gov/pubmed/26978795 http://dx.doi.org/10.7554/eLife.14319

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