rCGH: a comprehensive array-based genomic profile platform for precision medicine

Summary: We present rCGH, a comprehensive array-based comparative genomic hybridization analysis workflow, integrating computational improvements and functionalities specifically designed for precision medicine. rCGH supports the major microarray platforms, ensures a full traceability and facilitate...

Descripción completa

Detalles Bibliográficos
Autores principales: Commo, Frederic, Guinney, Justin, Ferté, Charles, Bot, Brian, Lefebvre, Celine, Soria, Jean-Charles, André, Fabrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848396/
https://www.ncbi.nlm.nih.gov/pubmed/26708336
http://dx.doi.org/10.1093/bioinformatics/btv718
Descripción
Sumario:Summary: We present rCGH, a comprehensive array-based comparative genomic hybridization analysis workflow, integrating computational improvements and functionalities specifically designed for precision medicine. rCGH supports the major microarray platforms, ensures a full traceability and facilitates profiles interpretation and decision-making through sharable interactive visualizations. Availability and implementation: The rCGH R package is available on bioconductor (under Artistic-2.0). The aCGH-viewer is available at https://fredcommo.shinyapps.io/aCGH_viewer, and the application implementation is freely available for installation at https://github.com/fredcommo/aCGH_viewer. Contact: frederic.commo@gustaveroussy.fr Supplementary information: Supplementary data are available at Bioinformatics online.

Ejemplares similares