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rCGH: a comprehensive array-based genomic profile platform for precision medicine

Summary: We present rCGH, a comprehensive array-based comparative genomic hybridization analysis workflow, integrating computational improvements and functionalities specifically designed for precision medicine. rCGH supports the major microarray platforms, ensures a full traceability and facilitate...

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Detalles Bibliográficos
Autores principales: Commo, Frederic, Guinney, Justin, Ferté, Charles, Bot, Brian, Lefebvre, Celine, Soria, Jean-Charles, André, Fabrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848396/
https://www.ncbi.nlm.nih.gov/pubmed/26708336
http://dx.doi.org/10.1093/bioinformatics/btv718
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author Commo, Frederic
Guinney, Justin
Ferté, Charles
Bot, Brian
Lefebvre, Celine
Soria, Jean-Charles
André, Fabrice
author_facet Commo, Frederic
Guinney, Justin
Ferté, Charles
Bot, Brian
Lefebvre, Celine
Soria, Jean-Charles
André, Fabrice
author_sort Commo, Frederic
collection PubMed
description Summary: We present rCGH, a comprehensive array-based comparative genomic hybridization analysis workflow, integrating computational improvements and functionalities specifically designed for precision medicine. rCGH supports the major microarray platforms, ensures a full traceability and facilitates profiles interpretation and decision-making through sharable interactive visualizations. Availability and implementation: The rCGH R package is available on bioconductor (under Artistic-2.0). The aCGH-viewer is available at https://fredcommo.shinyapps.io/aCGH_viewer, and the application implementation is freely available for installation at https://github.com/fredcommo/aCGH_viewer. Contact: frederic.commo@gustaveroussy.fr Supplementary information: Supplementary data are available at Bioinformatics online.
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spelling pubmed-48483962016-04-29 rCGH: a comprehensive array-based genomic profile platform for precision medicine Commo, Frederic Guinney, Justin Ferté, Charles Bot, Brian Lefebvre, Celine Soria, Jean-Charles André, Fabrice Bioinformatics Applications Notes Summary: We present rCGH, a comprehensive array-based comparative genomic hybridization analysis workflow, integrating computational improvements and functionalities specifically designed for precision medicine. rCGH supports the major microarray platforms, ensures a full traceability and facilitates profiles interpretation and decision-making through sharable interactive visualizations. Availability and implementation: The rCGH R package is available on bioconductor (under Artistic-2.0). The aCGH-viewer is available at https://fredcommo.shinyapps.io/aCGH_viewer, and the application implementation is freely available for installation at https://github.com/fredcommo/aCGH_viewer. Contact: frederic.commo@gustaveroussy.fr Supplementary information: Supplementary data are available at Bioinformatics online. Oxford University Press 2016-05-01 2015-12-26 /pmc/articles/PMC4848396/ /pubmed/26708336 http://dx.doi.org/10.1093/bioinformatics/btv718 Text en © The Author 2015. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Applications Notes
Commo, Frederic
Guinney, Justin
Ferté, Charles
Bot, Brian
Lefebvre, Celine
Soria, Jean-Charles
André, Fabrice
rCGH: a comprehensive array-based genomic profile platform for precision medicine
title rCGH: a comprehensive array-based genomic profile platform for precision medicine
title_full rCGH: a comprehensive array-based genomic profile platform for precision medicine
title_fullStr rCGH: a comprehensive array-based genomic profile platform for precision medicine
title_full_unstemmed rCGH: a comprehensive array-based genomic profile platform for precision medicine
title_short rCGH: a comprehensive array-based genomic profile platform for precision medicine
title_sort rcgh: a comprehensive array-based genomic profile platform for precision medicine
topic Applications Notes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848396/
https://www.ncbi.nlm.nih.gov/pubmed/26708336
http://dx.doi.org/10.1093/bioinformatics/btv718
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