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rCGH: a comprehensive array-based genomic profile platform for precision medicine
Summary: We present rCGH, a comprehensive array-based comparative genomic hybridization analysis workflow, integrating computational improvements and functionalities specifically designed for precision medicine. rCGH supports the major microarray platforms, ensures a full traceability and facilitate...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848396/ https://www.ncbi.nlm.nih.gov/pubmed/26708336 http://dx.doi.org/10.1093/bioinformatics/btv718 |
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author | Commo, Frederic Guinney, Justin Ferté, Charles Bot, Brian Lefebvre, Celine Soria, Jean-Charles André, Fabrice |
author_facet | Commo, Frederic Guinney, Justin Ferté, Charles Bot, Brian Lefebvre, Celine Soria, Jean-Charles André, Fabrice |
author_sort | Commo, Frederic |
collection | PubMed |
description | Summary: We present rCGH, a comprehensive array-based comparative genomic hybridization analysis workflow, integrating computational improvements and functionalities specifically designed for precision medicine. rCGH supports the major microarray platforms, ensures a full traceability and facilitates profiles interpretation and decision-making through sharable interactive visualizations. Availability and implementation: The rCGH R package is available on bioconductor (under Artistic-2.0). The aCGH-viewer is available at https://fredcommo.shinyapps.io/aCGH_viewer, and the application implementation is freely available for installation at https://github.com/fredcommo/aCGH_viewer. Contact: frederic.commo@gustaveroussy.fr Supplementary information: Supplementary data are available at Bioinformatics online. |
format | Online Article Text |
id | pubmed-4848396 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-48483962016-04-29 rCGH: a comprehensive array-based genomic profile platform for precision medicine Commo, Frederic Guinney, Justin Ferté, Charles Bot, Brian Lefebvre, Celine Soria, Jean-Charles André, Fabrice Bioinformatics Applications Notes Summary: We present rCGH, a comprehensive array-based comparative genomic hybridization analysis workflow, integrating computational improvements and functionalities specifically designed for precision medicine. rCGH supports the major microarray platforms, ensures a full traceability and facilitates profiles interpretation and decision-making through sharable interactive visualizations. Availability and implementation: The rCGH R package is available on bioconductor (under Artistic-2.0). The aCGH-viewer is available at https://fredcommo.shinyapps.io/aCGH_viewer, and the application implementation is freely available for installation at https://github.com/fredcommo/aCGH_viewer. Contact: frederic.commo@gustaveroussy.fr Supplementary information: Supplementary data are available at Bioinformatics online. Oxford University Press 2016-05-01 2015-12-26 /pmc/articles/PMC4848396/ /pubmed/26708336 http://dx.doi.org/10.1093/bioinformatics/btv718 Text en © The Author 2015. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Applications Notes Commo, Frederic Guinney, Justin Ferté, Charles Bot, Brian Lefebvre, Celine Soria, Jean-Charles André, Fabrice rCGH: a comprehensive array-based genomic profile platform for precision medicine |
title | rCGH: a comprehensive array-based genomic profile platform for precision medicine |
title_full | rCGH: a comprehensive array-based genomic profile platform for precision medicine |
title_fullStr | rCGH: a comprehensive array-based genomic profile platform for precision medicine |
title_full_unstemmed | rCGH: a comprehensive array-based genomic profile platform for precision medicine |
title_short | rCGH: a comprehensive array-based genomic profile platform for precision medicine |
title_sort | rcgh: a comprehensive array-based genomic profile platform for precision medicine |
topic | Applications Notes |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848396/ https://www.ncbi.nlm.nih.gov/pubmed/26708336 http://dx.doi.org/10.1093/bioinformatics/btv718 |
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