Posttranslational Modifications and the Immunogenicity of Biotherapeutics

Whilst the amino acid sequence of a protein is determined by its gene sequence, the final structure and function are determined by posttranslational modifications (PTMs), including quality control (QC) in the endoplasmic reticulum (ER) and during passage through the Golgi apparatus. These processes...

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Detalles Bibliográficos
Autor principal: Jefferis, Roy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848426/
https://www.ncbi.nlm.nih.gov/pubmed/27191002
http://dx.doi.org/10.1155/2016/5358272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848426/
https://www.ncbi.nlm.nih.gov/pubmed/27191002
http://dx.doi.org/10.1155/2016/5358272

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