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High-resolution analytical imaging and electron holography of magnetite particles in amyloid cores of Alzheimer’s disease
Abnormal accumulation of brain metals is a key feature of Alzheimer’s disease (AD). Formation of amyloid-β plaque cores (APC) is related to interactions with biometals, especially Fe, Cu and Zn, but their particular structural associations and roles remain unclear. Using an integrative set of advanc...
Autores principales: | Plascencia-Villa, Germán, Ponce, Arturo, Collingwood, Joanna F., Arellano-Jiménez, M. Josefina, Zhu, Xiongwei, Rogers, Jack T., Betancourt, Israel, José-Yacamán, Miguel, Perry, George |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848473/ https://www.ncbi.nlm.nih.gov/pubmed/27121137 http://dx.doi.org/10.1038/srep24873 |
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