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Mechanical cell competition kills cells via induction of lethal p53 levels

Cell competition is a quality control mechanism that eliminates unfit cells. How cells compete is poorly understood, but it is generally accepted that molecular exchange between cells signals elimination of unfit cells. Here we report an orthogonal mechanism of cell competition, whereby cells compet...

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Detalles Bibliográficos
Autores principales: Wagstaff, Laura, Goschorska, Maja, Kozyrska, Kasia, Duclos, Guillaume, Kucinski, Iwo, Chessel, Anatole, Hampton-O'Neil, Lea, Bradshaw, Charles R., Allen, George E., Rawlins, Emma L., Silberzan, Pascal, Carazo Salas, Rafael E., Piddini, Eugenia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848481/
https://www.ncbi.nlm.nih.gov/pubmed/27109213
http://dx.doi.org/10.1038/ncomms11373