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Cancer stem cells are underestimated by standard experimental methods in clear cell renal cell carcinoma

Rare cancer stem cells (CSC) are proposed to be responsible for tumour propagation and re-initiation and are functionally defined by identifying tumour-initiating cells (TICs) using the xenotransplantation limiting dilution assay (LDA). While TICs in clear cell renal cell carcinoma (ccRCC) appeared...

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Detalles Bibliográficos
Autores principales: Gedye, Craig, Sirskyj, Danylo, Lobo, Nazleen C., Meens, Jalna, Hyatt, Elzbieta, Robinette, Michael, Fleshner, Neil, Hamilton, Robert J, Kulkarni, Girish, Zlotta, Alexandre, Evans, Andrew, Finelli, Antonio, Jewett, Michael A. S., Ailles, Laurie E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848484/
https://www.ncbi.nlm.nih.gov/pubmed/27121191
http://dx.doi.org/10.1038/srep25220