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Identification of a Potent and Broad-Spectrum Hepatitis C Virus Fusion Inhibitory Peptide from the E2 Stem Domain

Hepatitis C virus (HCV) envelope proteins E1 and E2 play an essential role in virus entry. However, the fusion mechanisms of HCV remain largely unclear, hampering the development of efficient fusion inhibitors. Here, we developed two cell-based membrane fusion models that allow for screening a pepti...

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Detalles Bibliográficos
Autores principales:	Chi, Xiaojing, Niu, Yuqiang, Cheng, Min, Liu, Xiuying, Feng, Yetong, Zheng, Fuxiang, Fan, Jingjing, Li, Xiang, Jin, Qi, Zhong, Jin, Li, Yi-Ping, Yang, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848495/ https://www.ncbi.nlm.nih.gov/pubmed/27121372 http://dx.doi.org/10.1038/srep25224

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