Cargando…
The early history and emergence of molecular functions and modular scale-free network behavior
The formation of protein structural domains requires that biochemical functions, defined by conserved amino acid sequence motifs, be embedded into a structural scaffold. Here we trace domain history onto a bipartite network of elementary functional loop sequences and domain structures defined at the...
Autores principales: | Aziz, M. Fayez, Caetano-Anollés, Kelsey, Caetano-Anollés, Gustavo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848518/ https://www.ncbi.nlm.nih.gov/pubmed/27121452 http://dx.doi.org/10.1038/srep25058 |
Ejemplares similares
-
Emergence of Hierarchical Modularity in Evolving Networks Uncovered
by Phylogenomic Analysis
por: Caetano-Anollés, Gustavo, et al.
Publicado: (2019) -
MANET 3.0: Hierarchy and modularity in evolving metabolic networks
por: Mughal, Fizza, et al.
Publicado: (2019) -
Evolution of networks of protein domain organization
por: Aziz, M. Fayez, et al.
Publicado: (2021) -
Commentary: History of the ribosome and the origin of translation
por: Caetano-Anollés, Derek, et al.
Publicado: (2017) -
Structural Phylogenomics Reveals Gradual Evolutionary Replacement of Abiotic Chemistries by Protein Enzymes in Purine Metabolism
por: Caetano-Anollés, Kelsey, et al.
Publicado: (2013)