Using ultra-sensitive next generation sequencing to dissect DNA damage-induced mutagenesis

Next generation sequencing (NGS) technologies have dramatically improved studies in biology and biomedical science. However, no optimal NGS approach is available to conveniently analyze low frequency mutations caused by DNA damage treatments. Here, by developing an exquisite ultra-sensitive NGS (USN...

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Detalles Bibliográficos
Autores principales: Wang, Kaile, Ma, Xiaolu, Zhang, Xue, Wu, Dafei, Sun, Chenyi, Sun, Yazhou, Lu, Xuemei, Wu, Chung-I, Guo, Caixia, Ruan, Jue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848531/
https://www.ncbi.nlm.nih.gov/pubmed/27122023
http://dx.doi.org/10.1038/srep25310

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