Cargando…
A genetic basis for the variation in the vulnerability of cancer to DNA damage
Radiotherapy is not currently informed by the genetic composition of an individual patient's tumour. To identify genetic features regulating survival after DNA damage, here we conduct large-scale profiling of cellular survival after exposure to radiation in a diverse collection of 533 genetical...
Autores principales: | Yard, Brian D., Adams, Drew J., Chie, Eui Kyu, Tamayo, Pablo, Battaglia, Jessica S., Gopal, Priyanka, Rogacki, Kevin, Pearson, Bradley E., Phillips, James, Raymond, Daniel P., Pennell, Nathan A., Almeida, Francisco, Cheah, Jaime H., Clemons, Paul A., Shamji, Alykhan, Peacock, Craig D., Schreiber, Stuart L., Hammerman, Peter S., Abazeed, Mohamed E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848553/ https://www.ncbi.nlm.nih.gov/pubmed/27109210 http://dx.doi.org/10.1038/ncomms11428 |
Ejemplares similares
-
Multivalent state transitions shape the intratumoral composition of small cell lung carcinoma
por: Gopal, Priyanka, et al.
Publicado: (2022) -
The Mutational Landscape of Cancer's Vulnerability to Ionizing Radiation
por: Gopal, Priyanka, et al.
Publicado: (2022) -
NAMPT Is the Cellular Target of STF-31-Like Small-Molecule
Probes
por: Adams, Drew J., et al.
Publicado: (2014) -
Clonal selection confers distinct evolutionary trajectories in BRAF-driven cancers
por: Gopal, Priyanka, et al.
Publicado: (2019) -
A Small-Molecule Probe
of the Histone Methyltransferase
G9a Induces Cellular Senescence in Pancreatic Adenocarcinoma
por: Yuan, Yuan, et al.
Publicado: (2012)