Consequences of point mutations in melanoma-associated antigen 4 (MAGE-A4) protein: Insights from structural and biophysical studies

The Melanoma-Associated Antigen A4 (MAGE-A4) protein is a target for cancer therapy. The function of this protein is not well understood. We report the first comprehensive study on key cancer-associated MAGE-A4 mutations and provide analysis on the consequences of these mutations on the structure, f...

Descripción completa

Detalles Bibliográficos
Autores principales: Hagiwara, Yoshio, Sieverling, Lina, Hanif , Farina, Anton, Jensy, Dickinson, Eleanor R., Bui, Tam T. T., Andreeva, Antonina, Barran, Perdita E., Cota, Ernesto, Nikolova, Penka V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848555/
https://www.ncbi.nlm.nih.gov/pubmed/27121989
http://dx.doi.org/10.1038/srep25182

Ejemplares similares

Ejemplares similares