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Recombinant Pseudorabies Virus (PRV) Expressing Firefly Luciferase Effectively Screened for CRISPR/Cas9 Single Guide RNAs and Antiviral Compounds

A Pseudorabies virus (PRV) variant has emerged in China since 2011 that is not protected by commercial vaccines, and has not been well studied. The PRV genome is large and difficult to manipulate, but it is feasible to use clustered, regularly interspaced short palindromic repeats (CRISPR)/Cas9 tech...

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Detalles Bibliográficos
Autores principales:	Tang, Yan-Dong, Liu, Ji-Ting, Fang, Qiong-Qiong, Wang, Tong-Yun, Sun, Ming-Xia, An, Tong-Qing, Tian, Zhi-Jun, Cai, Xue-Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848585/ https://www.ncbi.nlm.nih.gov/pubmed/27043610 http://dx.doi.org/10.3390/v8040090

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