Accurate Extraction of Nanometer Distances in Multimers by Pulse EPR

Pulse electron paramagnetic resonance (EPR) is gaining increasing importance in structural biology. The PELDOR (pulsed electron–electron double resonance) method allows extracting distance information on the nanometer scale. Here, we demonstrate the efficient extraction of distances from multimeric...

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Detalles Bibliográficos
Autores principales: Valera, Silvia, Ackermann, Katrin, Pliotas, Christos, Huang, Hexian, Naismith, James H., Bode, Bela E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848767/
https://www.ncbi.nlm.nih.gov/pubmed/26865468
http://dx.doi.org/10.1002/chem.201505143
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author Valera, Silvia
Ackermann, Katrin
Pliotas, Christos
Huang, Hexian
Naismith, James H.
Bode, Bela E.
author_facet Valera, Silvia
Ackermann, Katrin
Pliotas, Christos
Huang, Hexian
Naismith, James H.
Bode, Bela E.
author_sort Valera, Silvia
collection PubMed
description Pulse electron paramagnetic resonance (EPR) is gaining increasing importance in structural biology. The PELDOR (pulsed electron–electron double resonance) method allows extracting distance information on the nanometer scale. Here, we demonstrate the efficient extraction of distances from multimeric systems such as membrane‐embedded ion channels where data analysis is commonly hindered by multi‐spin effects.
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spelling pubmed-48487672016-06-22 Accurate Extraction of Nanometer Distances in Multimers by Pulse EPR Valera, Silvia Ackermann, Katrin Pliotas, Christos Huang, Hexian Naismith, James H. Bode, Bela E. Chemistry Communications Pulse electron paramagnetic resonance (EPR) is gaining increasing importance in structural biology. The PELDOR (pulsed electron–electron double resonance) method allows extracting distance information on the nanometer scale. Here, we demonstrate the efficient extraction of distances from multimeric systems such as membrane‐embedded ion channels where data analysis is commonly hindered by multi‐spin effects. John Wiley and Sons Inc. 2016-02-25 2016-03-24 /pmc/articles/PMC4848767/ /pubmed/26865468 http://dx.doi.org/10.1002/chem.201505143 Text en © 2016 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Communications
Valera, Silvia
Ackermann, Katrin
Pliotas, Christos
Huang, Hexian
Naismith, James H.
Bode, Bela E.
Accurate Extraction of Nanometer Distances in Multimers by Pulse EPR
title Accurate Extraction of Nanometer Distances in Multimers by Pulse EPR
title_full Accurate Extraction of Nanometer Distances in Multimers by Pulse EPR
title_fullStr Accurate Extraction of Nanometer Distances in Multimers by Pulse EPR
title_full_unstemmed Accurate Extraction of Nanometer Distances in Multimers by Pulse EPR
title_short Accurate Extraction of Nanometer Distances in Multimers by Pulse EPR
title_sort accurate extraction of nanometer distances in multimers by pulse epr
topic Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848767/
https://www.ncbi.nlm.nih.gov/pubmed/26865468
http://dx.doi.org/10.1002/chem.201505143
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