Epigenetic assimilation in the aging human brain

BACKGROUND: Epigenetic drift progressively increases variation in DNA modification profiles of aging cells, but the finale of such divergence remains elusive. In this study, we explored the dynamics of DNA modification and transcription in the later stages of human life. RESULTS: We find that brain...

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Detalles Bibliográficos
Autores principales: Oh, Gabriel, Ebrahimi, Sasha, Wang, Sun-Chong, Cortese, Rene, Kaminsky, Zachary A., Gottesman, Irving I., Burke, James R., Plassman, Brenda L., Petronis, Art
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848814/
https://www.ncbi.nlm.nih.gov/pubmed/27122015
http://dx.doi.org/10.1186/s13059-016-0946-8

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