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Rhus verniciflua Stokes (RVS) and butein induce apoptosis of paclitaxel-resistant SKOV-3/PAX ovarian cancer cells through inhibition of AKT phosphorylation
BACKGROUND: Rhus verniciflua Stokes (RVS) belongs to the Anacardiaceae family and traditionally used for cancer treatment. RVS and butein, a major compound of RVS, were known to induce apoptosis via AKT inhibition in cancer cells. Thus, in this study, we investigated the effect of RVS and its deriva...
Autores principales: | Choi, Hyeong Sim, Kim, Min Kyoung, Choi, Youn Kyung, Shin, Yong Cheol, Cho, Sung-Gook, Ko, Seong-Gyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848824/ https://www.ncbi.nlm.nih.gov/pubmed/27121110 http://dx.doi.org/10.1186/s12906-016-1103-3 |
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