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Multisystem reactions during egg oral food challenges may be associated with less severe reactions on initial presentation

In this study, we assessed whether multisystem reactions to egg and extensively-heated (EH) egg during OFCs were associated with a history of multisystem reactions. Records of children, who underwent OFC to egg or EH egg over a five-year period were reviewed. Of the 120 challenges, 26 (21.67 %) fail...

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Autores principales: Vitalpur, Girish, Esquivel, Ann, Kloepfer, Kirsten M., Slaven, James E., Leickly, Frederick E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848849/
https://www.ncbi.nlm.nih.gov/pubmed/27127527
http://dx.doi.org/10.1186/s13223-016-0125-1
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author Vitalpur, Girish
Esquivel, Ann
Kloepfer, Kirsten M.
Slaven, James E.
Leickly, Frederick E.
author_facet Vitalpur, Girish
Esquivel, Ann
Kloepfer, Kirsten M.
Slaven, James E.
Leickly, Frederick E.
author_sort Vitalpur, Girish
collection PubMed
description In this study, we assessed whether multisystem reactions to egg and extensively-heated (EH) egg during OFCs were associated with a history of multisystem reactions. Records of children, who underwent OFC to egg or EH egg over a five-year period were reviewed. Of the 120 challenges, 26 (21.67 %) failed, with 38.4 % (10/26) having multisystem reactions. Of the 13 who had multisystem reactions on initial presentation, only two (15.4 %) had a similar OFC outcome. Eighty percent (8/10) of those who had a multisystem OFC reaction had a less severe initial presentation. Initial and OFC multisystem reactions were not associated with each other.
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spelling pubmed-48488492016-04-29 Multisystem reactions during egg oral food challenges may be associated with less severe reactions on initial presentation Vitalpur, Girish Esquivel, Ann Kloepfer, Kirsten M. Slaven, James E. Leickly, Frederick E. Allergy Asthma Clin Immunol Letter to the Editor In this study, we assessed whether multisystem reactions to egg and extensively-heated (EH) egg during OFCs were associated with a history of multisystem reactions. Records of children, who underwent OFC to egg or EH egg over a five-year period were reviewed. Of the 120 challenges, 26 (21.67 %) failed, with 38.4 % (10/26) having multisystem reactions. Of the 13 who had multisystem reactions on initial presentation, only two (15.4 %) had a similar OFC outcome. Eighty percent (8/10) of those who had a multisystem OFC reaction had a less severe initial presentation. Initial and OFC multisystem reactions were not associated with each other. BioMed Central 2016-04-28 /pmc/articles/PMC4848849/ /pubmed/27127527 http://dx.doi.org/10.1186/s13223-016-0125-1 Text en © Vitalpur et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Letter to the Editor
Vitalpur, Girish
Esquivel, Ann
Kloepfer, Kirsten M.
Slaven, James E.
Leickly, Frederick E.
Multisystem reactions during egg oral food challenges may be associated with less severe reactions on initial presentation
title Multisystem reactions during egg oral food challenges may be associated with less severe reactions on initial presentation
title_full Multisystem reactions during egg oral food challenges may be associated with less severe reactions on initial presentation
title_fullStr Multisystem reactions during egg oral food challenges may be associated with less severe reactions on initial presentation
title_full_unstemmed Multisystem reactions during egg oral food challenges may be associated with less severe reactions on initial presentation
title_short Multisystem reactions during egg oral food challenges may be associated with less severe reactions on initial presentation
title_sort multisystem reactions during egg oral food challenges may be associated with less severe reactions on initial presentation
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848849/
https://www.ncbi.nlm.nih.gov/pubmed/27127527
http://dx.doi.org/10.1186/s13223-016-0125-1
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