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Zoledronic acid in metastatic osteosarcoma: encouraging progression free survival in four consecutive patients
BACKGROUND: Zoledronic acid (ZA) is a third-generation bisphosphonate in widespread clinical use to reduce pain and skeletal events in patients from a variety of malignancies with bone metastases. Pre-clinical studies indicate that ZA inhibits osteosarcoma through direct anti-proliferative effects,...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848872/ https://www.ncbi.nlm.nih.gov/pubmed/27127605 http://dx.doi.org/10.1186/s13569-016-0046-2 |