Targeted Disruption of Melanin Biosynthesis Genes in the Human Pathogenic Fungus Lomentospora prolificans and Its Consequences for Pathogen Survival

The dematiaceous (melanised) fungus Lomentospora (Scedosporium) prolificans is a life-threatening opportunistic pathogen of immunocompromised humans, resistant to anti-fungal drugs. Melanin has been shown to protect human pathogenic fungi against antifungal drugs, oxidative killing and environmental...

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Detalles Bibliográficos
Autores principales: Al-Laaeiby, Ayat, Kershaw, Michael J., Penn, Tina J., Thornton, Christopher R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848900/
https://www.ncbi.nlm.nih.gov/pubmed/27023523
http://dx.doi.org/10.3390/ijms17040444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848900/
https://www.ncbi.nlm.nih.gov/pubmed/27023523
http://dx.doi.org/10.3390/ijms17040444

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