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Distinct Dasatinib-Induced Mechanisms of Apoptotic Response and Exosome Release in Imatinib-Resistant Human Chronic Myeloid Leukemia Cells
Although dasatinib is effective in most imatinib mesylate (IMT)-resistant chronic myeloid leukemia (CML) patients, the underlying mechanism of its effectiveness in eliminating imatinib-resistant cells is only partially understood. This study investigated the effects of dasatinib on signaling mechani...
Autores principales: | Liu, Juan, Zhang, Yujing, Liu, Aichun, Wang, Jinghua, Li, Lianqiao, Chen, Xi, Gao, Xinyu, Xue, Yanming, Zhang, Xiaomin, Liu, Yao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848987/ https://www.ncbi.nlm.nih.gov/pubmed/27070592 http://dx.doi.org/10.3390/ijms17040531 |
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