Pancreatic Transdifferentiation and Glucose-Regulated Production of Human Insulin in the H4IIE Rat Liver Cell Line

Due to the limitations of current treatment regimes, gene therapy is a promising strategy being explored to correct blood glucose concentrations in diabetic patients. In the current study, we used a retroviral vector to deliver either the human insulin gene alone, the rat NeuroD1 gene alone, or the...

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Detalles Bibliográficos
Autores principales: Ren, Binhai, Tao, Chang, Swan, Margaret Anne, Joachim, Nichole, Martiniello-Wilks, Rosetta, Nassif, Najah T., O’Brien, Bronwyn A., Simpson, Ann M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848990/
https://www.ncbi.nlm.nih.gov/pubmed/27070593
http://dx.doi.org/10.3390/ijms17040534

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