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Linkers Having a Crucial Role in Antibody–Drug Conjugates

Antibody–drug conjugates (ADCs) comprised of a desirable monoclonal antibody, an active cytotoxic drug and an appropriate linker are considered to be an innovative therapeutic approach for targeted treatment of various types of tumors and cancers, enhancing the therapeutic parameter of the cytotoxic...

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Detalles Bibliográficos
Autores principales: Lu, Jun, Jiang, Feng, Lu, Aiping, Zhang, Ge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849017/
https://www.ncbi.nlm.nih.gov/pubmed/27089329
http://dx.doi.org/10.3390/ijms17040561