Cargando…
Linkers Having a Crucial Role in Antibody–Drug Conjugates
Antibody–drug conjugates (ADCs) comprised of a desirable monoclonal antibody, an active cytotoxic drug and an appropriate linker are considered to be an innovative therapeutic approach for targeted treatment of various types of tumors and cancers, enhancing the therapeutic parameter of the cytotoxic...
Autores principales: | Lu, Jun, Jiang, Feng, Lu, Aiping, Zhang, Ge |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849017/ https://www.ncbi.nlm.nih.gov/pubmed/27089329 http://dx.doi.org/10.3390/ijms17040561 |
Ejemplares similares
-
Methods to Design and Synthesize Antibody-Drug Conjugates (ADCs)
por: Yao, Houzong, et al.
Publicado: (2016) -
Antibody-drug conjugates: recent advances in conjugation and linker chemistries
por: Tsuchikama, Kyoji, et al.
Publicado: (2016) -
Linkers: An Assurance for Controlled Delivery of Antibody-Drug Conjugate
por: Sheyi, Rotimi, et al.
Publicado: (2022) -
Antibody–drug conjugates: Recent advances in linker chemistry
por: Su, Zheng, et al.
Publicado: (2021) -
Lysosomal-Cleavable Peptide Linkers in Antibody–Drug Conjugates
por: Balamkundu, Seetharamsing, et al.
Publicado: (2023)