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Piperlongumine Suppresses Proliferation of Human Oral Squamous Cell Carcinoma through Cell Cycle Arrest, Apoptosis and Senescence

Oral squamous cell carcinoma (OSCC), an aggressive cancer originating in the oral cavity, is one of the leading causes of cancer deaths in males worldwide. This study investigated the antitumor activity and mechanisms of piperlongumine (PL), a natural compound isolated from Piper longum L., in human...

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Detalles Bibliográficos
Autores principales: Chen, San-Yuan, Liu, Geng-Hung, Chao, Wen-Ying, Shi, Chung-Sheng, Lin, Ching-Yen, Lim, Yun-Ping, Lu, Chieh-Hsiang, Lai, Peng-Yeh, Chen, Hau-Ren, Lee, Ying-Ray
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849064/
https://www.ncbi.nlm.nih.gov/pubmed/27120594
http://dx.doi.org/10.3390/ijms17040616

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