Cargando…
Piperlongumine Suppresses Proliferation of Human Oral Squamous Cell Carcinoma through Cell Cycle Arrest, Apoptosis and Senescence
Oral squamous cell carcinoma (OSCC), an aggressive cancer originating in the oral cavity, is one of the leading causes of cancer deaths in males worldwide. This study investigated the antitumor activity and mechanisms of piperlongumine (PL), a natural compound isolated from Piper longum L., in human...
Autores principales: | Chen, San-Yuan, Liu, Geng-Hung, Chao, Wen-Ying, Shi, Chung-Sheng, Lin, Ching-Yen, Lim, Yun-Ping, Lu, Chieh-Hsiang, Lai, Peng-Yeh, Chen, Hau-Ren, Lee, Ying-Ray |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849064/ https://www.ncbi.nlm.nih.gov/pubmed/27120594 http://dx.doi.org/10.3390/ijms17040616 |
Ejemplares similares
-
Piperlongumine, a Potent Anticancer Phytotherapeutic, Induces Cell Cycle Arrest and Apoptosis In Vitro and In Vivo through the ROS/Akt Pathway in Human Thyroid Cancer Cells
por: Kung, Fang-Ping, et al.
Publicado: (2021) -
Reversine suppresses oral squamous cell carcinoma via cell cycle arrest and concomitantly apoptosis and autophagy
por: Lee, Ying-Ray, et al.
Publicado: (2012) -
Honokiol inhibits in vitro and in vivo growth of oral squamous cell carcinoma through induction of apoptosis, cell cycle arrest and autophagy
por: Huang, Kao‐Jean, et al.
Publicado: (2018) -
Cell cycle arrest is not senescence
por: Blagosklonny, Mikhail V.
Publicado: (2011) -
Piperlongumine Induces Cell Cycle Arrest via Reactive Oxygen Species Accumulation and IKKβ Suppression in Human Breast Cancer Cells
por: Jeong, Chang Hee, et al.
Publicado: (2019)