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Comparison of Serum Calcium and Magnesium Between Preeclamptic and Normotensive Pregnant Nigerian Women in Abakaliki, Nigeria
BACKGROUND: Evidence suggests the involvement of calcium and magnesium metabolism in the pathophysiology of preeclampsia. However, findings from studies are heterogenous and inconsistent. AIM: The study aimed to compare the total serum calcium and magnesium levels in preeclamptic women with that of...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849113/ https://www.ncbi.nlm.nih.gov/pubmed/27144074 http://dx.doi.org/10.4103/2141-9248.180269 |
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author | Ugwuja, EI Famurewa, AC Ikaraoha, CI |
author_facet | Ugwuja, EI Famurewa, AC Ikaraoha, CI |
author_sort | Ugwuja, EI |
collection | PubMed |
description | BACKGROUND: Evidence suggests the involvement of calcium and magnesium metabolism in the pathophysiology of preeclampsia. However, findings from studies are heterogenous and inconsistent. AIM: The study aimed to compare the total serum calcium and magnesium levels in preeclamptic women with that of normotensive pregnant women. SUBJECTS AND METHODS: A cross-sectional subjects of eighty pregnant women living in Abakaliki, Ebonyi state, South-East Nigeria, were recruited into the study. The present study compared serum calcium and magnesium in forty preeclamptic (cases) and forty normotensive (control) pregnant women matched for age, parity, and socioeconomic status. Serum calcium and magnesium levels were measured using atomic absorption spectrophotometer. Statistical analysis was done using SPSS Version 20 statistical software. Differences between means were compared using Student's t-test with P < 0.05 considered as statistically significant. RESULTS: While the mean serum calcium was comparable between preeclamptic and normotensive pregnant women (13.99 [3.29] vs. 14.02 [5.68] μg/dl), the preeclamptic pregnant women have significantly (P < 0.001) lower serum magnesium in comparison to their normotensive counterparts (3.22 [1.05] vs. 4.15 [0.78]). CONCLUSION: It may be concluded that serum magnesium seems to play a crucial role in the pathophysiology of preeclampsia in this environment. |
format | Online Article Text |
id | pubmed-4849113 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-48491132016-05-03 Comparison of Serum Calcium and Magnesium Between Preeclamptic and Normotensive Pregnant Nigerian Women in Abakaliki, Nigeria Ugwuja, EI Famurewa, AC Ikaraoha, CI Ann Med Health Sci Res Original Article BACKGROUND: Evidence suggests the involvement of calcium and magnesium metabolism in the pathophysiology of preeclampsia. However, findings from studies are heterogenous and inconsistent. AIM: The study aimed to compare the total serum calcium and magnesium levels in preeclamptic women with that of normotensive pregnant women. SUBJECTS AND METHODS: A cross-sectional subjects of eighty pregnant women living in Abakaliki, Ebonyi state, South-East Nigeria, were recruited into the study. The present study compared serum calcium and magnesium in forty preeclamptic (cases) and forty normotensive (control) pregnant women matched for age, parity, and socioeconomic status. Serum calcium and magnesium levels were measured using atomic absorption spectrophotometer. Statistical analysis was done using SPSS Version 20 statistical software. Differences between means were compared using Student's t-test with P < 0.05 considered as statistically significant. RESULTS: While the mean serum calcium was comparable between preeclamptic and normotensive pregnant women (13.99 [3.29] vs. 14.02 [5.68] μg/dl), the preeclamptic pregnant women have significantly (P < 0.001) lower serum magnesium in comparison to their normotensive counterparts (3.22 [1.05] vs. 4.15 [0.78]). CONCLUSION: It may be concluded that serum magnesium seems to play a crucial role in the pathophysiology of preeclampsia in this environment. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC4849113/ /pubmed/27144074 http://dx.doi.org/10.4103/2141-9248.180269 Text en Copyright: © Annals of Medical and Health Sciences Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution NonCommercial ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Ugwuja, EI Famurewa, AC Ikaraoha, CI Comparison of Serum Calcium and Magnesium Between Preeclamptic and Normotensive Pregnant Nigerian Women in Abakaliki, Nigeria |
title | Comparison of Serum Calcium and Magnesium Between Preeclamptic and Normotensive Pregnant Nigerian Women in Abakaliki, Nigeria |
title_full | Comparison of Serum Calcium and Magnesium Between Preeclamptic and Normotensive Pregnant Nigerian Women in Abakaliki, Nigeria |
title_fullStr | Comparison of Serum Calcium and Magnesium Between Preeclamptic and Normotensive Pregnant Nigerian Women in Abakaliki, Nigeria |
title_full_unstemmed | Comparison of Serum Calcium and Magnesium Between Preeclamptic and Normotensive Pregnant Nigerian Women in Abakaliki, Nigeria |
title_short | Comparison of Serum Calcium and Magnesium Between Preeclamptic and Normotensive Pregnant Nigerian Women in Abakaliki, Nigeria |
title_sort | comparison of serum calcium and magnesium between preeclamptic and normotensive pregnant nigerian women in abakaliki, nigeria |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849113/ https://www.ncbi.nlm.nih.gov/pubmed/27144074 http://dx.doi.org/10.4103/2141-9248.180269 |
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