Inhibition of AKT promotes FOXO3a-dependent apoptosis in prostate cancer

Growth factor-induced activation of protein kinase-B (PKB), also known as AKT, induces pro-survival signaling and inhibits activation of pro-apoptotic signaling molecules including the Forkhead box O-3a (FOXO3a) transcription factor and caspase in transformed prostate cells in vitro. Earlier we repo...

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Detalles Bibliográficos
Autores principales: Das, T P, Suman, S, Alatassi, H, Ankem, M K, Damodaran, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849149/
https://www.ncbi.nlm.nih.gov/pubmed/26913603
http://dx.doi.org/10.1038/cddis.2015.403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849149/
https://www.ncbi.nlm.nih.gov/pubmed/26913603
http://dx.doi.org/10.1038/cddis.2015.403

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