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Structural simulation of adenosine phosphate via plumbagin and zoledronic acid competitively targets JNK/Erk to synergistically attenuate osteoclastogenesis in a breast cancer model

The treatment of breast cancer-induced osteolysis remains a challenge in clinical settings. Here, we explored the effect and mechanism of combined treatment with zoledronic acid (ZA) and plumbagin (PL), a widely investigated component derived from Plumbago zeylanica, against breast cancer-induced os...

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Detalles Bibliográficos
Autores principales:	Qiao, H, Wang, T-y, Yu, Z-f, Han, X-g, Liu, X-q, Wang, Y-g, Fan, Q-m, Qin, A, Tang, T-t
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849151/ https://www.ncbi.nlm.nih.gov/pubmed/26866274 http://dx.doi.org/10.1038/cddis.2016.11

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