Proteomic screening identifies calreticulin as a miR-27a direct target repressing MHC class I cell surface exposure in colorectal cancer

Impairment of the immune response and aberrant expression of microRNAs are emerging hallmarks of tumour initiation/progression, in addition to driver gene mutations and epigenetic modifications. We performed a preliminary survey of independent adenoma and colorectal cancer (CRC) miRnoma data sets an...

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Detalles Bibliográficos
Autores principales: Colangelo, T, Polcaro, G, Ziccardi, P, Pucci, B, Muccillo, L, Galgani, M, Fucci, A, Milone, M R, Budillon, A, Santopaolo, M, Votino, C, Pancione, M, Piepoli, A, Mazzoccoli, G, Binaschi, M, Bigioni, M, Maggi, C A, Fassan, M, Laudanna, C, Matarese, G, Sabatino, L, Colantuoni, V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849154/
https://www.ncbi.nlm.nih.gov/pubmed/26913609
http://dx.doi.org/10.1038/cddis.2016.28

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