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Transformation of a meningioma with atypical imaging
Meningiomas are benign tumors of the central nervous system. They have long term curability if they are excised completely. If not, they can recur after a prolonged period and can lead to increased morbidity during re-surgery. Recurrence is rarely associated with invasiveness. Usually de-differentia...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849313/ https://www.ncbi.nlm.nih.gov/pubmed/27366271 http://dx.doi.org/10.4103/1793-5482.145062 |
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author | Kumar, Ashish Deopujari, Chandrashekhar Karmarkar, Vikram |
author_facet | Kumar, Ashish Deopujari, Chandrashekhar Karmarkar, Vikram |
author_sort | Kumar, Ashish |
collection | PubMed |
description | Meningiomas are benign tumors of the central nervous system. They have long term curability if they are excised completely. If not, they can recur after a prolonged period and can lead to increased morbidity during re-surgery. Recurrence is rarely associated with invasiveness. Usually de-differentiation in case of meningiomas is uncommon without any predisposing factors including different genetic mutations or radiation to the involved region. We report a case of a 38-year-old female who was operated for a benign para-sagittal meningioma 8 years back and subsequently developed an invasive recurrence off late. Also this time, the imaging morphology was slightly different for a meningioma and gross as well as microscopic findings were very atypical. Awareness for such cases must be there while dealing with recurrent meningiomas as invasiveness may not always be associated with adverse predisposing factors like radiation. As invasiveness is always a histopathological diagnosis, picking up such features on imaging is a daunting task and if done, can help neurosurgeons prognosticate such invasive recurrences in a better fashion. |
format | Online Article Text |
id | pubmed-4849313 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-48493132016-07-01 Transformation of a meningioma with atypical imaging Kumar, Ashish Deopujari, Chandrashekhar Karmarkar, Vikram Asian J Neurosurg Case Report Meningiomas are benign tumors of the central nervous system. They have long term curability if they are excised completely. If not, they can recur after a prolonged period and can lead to increased morbidity during re-surgery. Recurrence is rarely associated with invasiveness. Usually de-differentiation in case of meningiomas is uncommon without any predisposing factors including different genetic mutations or radiation to the involved region. We report a case of a 38-year-old female who was operated for a benign para-sagittal meningioma 8 years back and subsequently developed an invasive recurrence off late. Also this time, the imaging morphology was slightly different for a meningioma and gross as well as microscopic findings were very atypical. Awareness for such cases must be there while dealing with recurrent meningiomas as invasiveness may not always be associated with adverse predisposing factors like radiation. As invasiveness is always a histopathological diagnosis, picking up such features on imaging is a daunting task and if done, can help neurosurgeons prognosticate such invasive recurrences in a better fashion. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC4849313/ /pubmed/27366271 http://dx.doi.org/10.4103/1793-5482.145062 Text en Copyright: © 2016 Asian Journal of Neurosurgery http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Kumar, Ashish Deopujari, Chandrashekhar Karmarkar, Vikram Transformation of a meningioma with atypical imaging |
title | Transformation of a meningioma with atypical imaging |
title_full | Transformation of a meningioma with atypical imaging |
title_fullStr | Transformation of a meningioma with atypical imaging |
title_full_unstemmed | Transformation of a meningioma with atypical imaging |
title_short | Transformation of a meningioma with atypical imaging |
title_sort | transformation of a meningioma with atypical imaging |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849313/ https://www.ncbi.nlm.nih.gov/pubmed/27366271 http://dx.doi.org/10.4103/1793-5482.145062 |
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