Cargando…

Transformation of a meningioma with atypical imaging

Meningiomas are benign tumors of the central nervous system. They have long term curability if they are excised completely. If not, they can recur after a prolonged period and can lead to increased morbidity during re-surgery. Recurrence is rarely associated with invasiveness. Usually de-differentia...

Descripción completa

Detalles Bibliográficos
Autores principales: Kumar, Ashish, Deopujari, Chandrashekhar, Karmarkar, Vikram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849313/
https://www.ncbi.nlm.nih.gov/pubmed/27366271
http://dx.doi.org/10.4103/1793-5482.145062
_version_ 1782429525350547456
author Kumar, Ashish
Deopujari, Chandrashekhar
Karmarkar, Vikram
author_facet Kumar, Ashish
Deopujari, Chandrashekhar
Karmarkar, Vikram
author_sort Kumar, Ashish
collection PubMed
description Meningiomas are benign tumors of the central nervous system. They have long term curability if they are excised completely. If not, they can recur after a prolonged period and can lead to increased morbidity during re-surgery. Recurrence is rarely associated with invasiveness. Usually de-differentiation in case of meningiomas is uncommon without any predisposing factors including different genetic mutations or radiation to the involved region. We report a case of a 38-year-old female who was operated for a benign para-sagittal meningioma 8 years back and subsequently developed an invasive recurrence off late. Also this time, the imaging morphology was slightly different for a meningioma and gross as well as microscopic findings were very atypical. Awareness for such cases must be there while dealing with recurrent meningiomas as invasiveness may not always be associated with adverse predisposing factors like radiation. As invasiveness is always a histopathological diagnosis, picking up such features on imaging is a daunting task and if done, can help neurosurgeons prognosticate such invasive recurrences in a better fashion.
format Online
Article
Text
id pubmed-4849313
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-48493132016-07-01 Transformation of a meningioma with atypical imaging Kumar, Ashish Deopujari, Chandrashekhar Karmarkar, Vikram Asian J Neurosurg Case Report Meningiomas are benign tumors of the central nervous system. They have long term curability if they are excised completely. If not, they can recur after a prolonged period and can lead to increased morbidity during re-surgery. Recurrence is rarely associated with invasiveness. Usually de-differentiation in case of meningiomas is uncommon without any predisposing factors including different genetic mutations or radiation to the involved region. We report a case of a 38-year-old female who was operated for a benign para-sagittal meningioma 8 years back and subsequently developed an invasive recurrence off late. Also this time, the imaging morphology was slightly different for a meningioma and gross as well as microscopic findings were very atypical. Awareness for such cases must be there while dealing with recurrent meningiomas as invasiveness may not always be associated with adverse predisposing factors like radiation. As invasiveness is always a histopathological diagnosis, picking up such features on imaging is a daunting task and if done, can help neurosurgeons prognosticate such invasive recurrences in a better fashion. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC4849313/ /pubmed/27366271 http://dx.doi.org/10.4103/1793-5482.145062 Text en Copyright: © 2016 Asian Journal of Neurosurgery http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Kumar, Ashish
Deopujari, Chandrashekhar
Karmarkar, Vikram
Transformation of a meningioma with atypical imaging
title Transformation of a meningioma with atypical imaging
title_full Transformation of a meningioma with atypical imaging
title_fullStr Transformation of a meningioma with atypical imaging
title_full_unstemmed Transformation of a meningioma with atypical imaging
title_short Transformation of a meningioma with atypical imaging
title_sort transformation of a meningioma with atypical imaging
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849313/
https://www.ncbi.nlm.nih.gov/pubmed/27366271
http://dx.doi.org/10.4103/1793-5482.145062
work_keys_str_mv AT kumarashish transformationofameningiomawithatypicalimaging
AT deopujarichandrashekhar transformationofameningiomawithatypicalimaging
AT karmarkarvikram transformationofameningiomawithatypicalimaging