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Aerobic exercise and yoga improve neurocognitive function in women with early psychosis

Impairments of attention and memory are evident in early psychosis, and are associated with functional disability. In a group of stable, medicated women patients, we aimed to determine whether participating in aerobic exercise or yoga improved cognitive impairments and clinical symptoms. A total of...

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Autores principales: Lin, Jingxia, Chan, Sherry KW, Lee, Edwin HM, Chang, Wing Chung, Tse, Michael, Su, Wayne Weizhong, Sham, Pak, Hui, Christy LM, Joe, Glen, Chan, Cecilia LW, Khong, P L, So, Kwok Fai, Honer, William G, Chen, Eric YH
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849465/
https://www.ncbi.nlm.nih.gov/pubmed/27336050
http://dx.doi.org/10.1038/npjschz.2015.47
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author Lin, Jingxia
Chan, Sherry KW
Lee, Edwin HM
Chang, Wing Chung
Tse, Michael
Su, Wayne Weizhong
Sham, Pak
Hui, Christy LM
Joe, Glen
Chan, Cecilia LW
Khong, P L
So, Kwok Fai
Honer, William G
Chen, Eric YH
author_facet Lin, Jingxia
Chan, Sherry KW
Lee, Edwin HM
Chang, Wing Chung
Tse, Michael
Su, Wayne Weizhong
Sham, Pak
Hui, Christy LM
Joe, Glen
Chan, Cecilia LW
Khong, P L
So, Kwok Fai
Honer, William G
Chen, Eric YH
author_sort Lin, Jingxia
collection PubMed
description Impairments of attention and memory are evident in early psychosis, and are associated with functional disability. In a group of stable, medicated women patients, we aimed to determine whether participating in aerobic exercise or yoga improved cognitive impairments and clinical symptoms. A total of 140 female patients were recruited, and 124 received the allocated intervention in a randomized controlled study of 12 weeks of yoga or aerobic exercise compared with a waitlist group. The primary outcomes were cognitive functions including memory and attention. Secondary outcome measures were the severity of psychotic and depressive symptoms, and hippocampal volume. Data from 124 patients were included in the final analysis based on the intention-to-treat principle. Both yoga and aerobic exercise groups demonstrated significant improvements in working memory (P<0.01) with moderate to large effect sizes compared with the waitlist control group. The yoga group showed additional benefits in verbal acquisition (P<0.01) and attention (P=0.01). Both types of exercise improved overall and depressive symptoms (all P⩽0.01) after 12 weeks. Small increases in hippocampal volume were observed in the aerobic exercise group compared with waitlist (P=0.01). Both types of exercise improved working memory in early psychosis patients, with yoga having a larger effect on verbal acquisition and attention than aerobic exercise. The application of yoga and aerobic exercise as adjunctive treatments for early psychosis merits serious consideration. This study was supported by the Small Research Funding of the University of Hong Kong (201007176229), and RGC funding (C00240/762412) by the Authority of Research, Hong Kong.
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spelling pubmed-48494652016-06-22 Aerobic exercise and yoga improve neurocognitive function in women with early psychosis Lin, Jingxia Chan, Sherry KW Lee, Edwin HM Chang, Wing Chung Tse, Michael Su, Wayne Weizhong Sham, Pak Hui, Christy LM Joe, Glen Chan, Cecilia LW Khong, P L So, Kwok Fai Honer, William G Chen, Eric YH NPJ Schizophr Article Impairments of attention and memory are evident in early psychosis, and are associated with functional disability. In a group of stable, medicated women patients, we aimed to determine whether participating in aerobic exercise or yoga improved cognitive impairments and clinical symptoms. A total of 140 female patients were recruited, and 124 received the allocated intervention in a randomized controlled study of 12 weeks of yoga or aerobic exercise compared with a waitlist group. The primary outcomes were cognitive functions including memory and attention. Secondary outcome measures were the severity of psychotic and depressive symptoms, and hippocampal volume. Data from 124 patients were included in the final analysis based on the intention-to-treat principle. Both yoga and aerobic exercise groups demonstrated significant improvements in working memory (P<0.01) with moderate to large effect sizes compared with the waitlist control group. The yoga group showed additional benefits in verbal acquisition (P<0.01) and attention (P=0.01). Both types of exercise improved overall and depressive symptoms (all P⩽0.01) after 12 weeks. Small increases in hippocampal volume were observed in the aerobic exercise group compared with waitlist (P=0.01). Both types of exercise improved working memory in early psychosis patients, with yoga having a larger effect on verbal acquisition and attention than aerobic exercise. The application of yoga and aerobic exercise as adjunctive treatments for early psychosis merits serious consideration. This study was supported by the Small Research Funding of the University of Hong Kong (201007176229), and RGC funding (C00240/762412) by the Authority of Research, Hong Kong. Nature Publishing Group 2015-12-02 /pmc/articles/PMC4849465/ /pubmed/27336050 http://dx.doi.org/10.1038/npjschz.2015.47 Text en Copyright © 2015 Schizophrenia International Research Society/Nature Publishing Group http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Lin, Jingxia
Chan, Sherry KW
Lee, Edwin HM
Chang, Wing Chung
Tse, Michael
Su, Wayne Weizhong
Sham, Pak
Hui, Christy LM
Joe, Glen
Chan, Cecilia LW
Khong, P L
So, Kwok Fai
Honer, William G
Chen, Eric YH
Aerobic exercise and yoga improve neurocognitive function in women with early psychosis
title Aerobic exercise and yoga improve neurocognitive function in women with early psychosis
title_full Aerobic exercise and yoga improve neurocognitive function in women with early psychosis
title_fullStr Aerobic exercise and yoga improve neurocognitive function in women with early psychosis
title_full_unstemmed Aerobic exercise and yoga improve neurocognitive function in women with early psychosis
title_short Aerobic exercise and yoga improve neurocognitive function in women with early psychosis
title_sort aerobic exercise and yoga improve neurocognitive function in women with early psychosis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849465/
https://www.ncbi.nlm.nih.gov/pubmed/27336050
http://dx.doi.org/10.1038/npjschz.2015.47
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