MicroRNA Seed Region Length Impact on Target Messenger RNA Expression and Survival in Colorectal Cancer

microRNAs (miRNA) repress messenger RNAs post-transcriptionally through binding to the 3’ UTR of the mRNA with the miRNA seed region. It has been purported that longer seed regions have a greater efficacy on mRNA repression. We tested this hypothesis by evaluating differential expression of miRNAs i...

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Detalles Bibliográficos
Autores principales: Mullany, Lila E., Herrick, Jennifer S., Wolff, Roger K., Slattery, Martha L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849741/
https://www.ncbi.nlm.nih.gov/pubmed/27123865
http://dx.doi.org/10.1371/journal.pone.0154177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849741/
https://www.ncbi.nlm.nih.gov/pubmed/27123865
http://dx.doi.org/10.1371/journal.pone.0154177

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