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MicroRNA Seed Region Length Impact on Target Messenger RNA Expression and Survival in Colorectal Cancer
microRNAs (miRNA) repress messenger RNAs post-transcriptionally through binding to the 3’ UTR of the mRNA with the miRNA seed region. It has been purported that longer seed regions have a greater efficacy on mRNA repression. We tested this hypothesis by evaluating differential expression of miRNAs i...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849741/ https://www.ncbi.nlm.nih.gov/pubmed/27123865 http://dx.doi.org/10.1371/journal.pone.0154177 |