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Transformed Recombinant Enrichment Profiling Rapidly Identifies HMW1 as an Intracellular Invasion Locus in Haemophilus influenzae

Many bacterial species actively take up and recombine homologous DNA into their genomes, called natural competence, a trait that offers a means to identify the genetic basis of naturally occurring phenotypic variation. Here, we describe “transformed recombinant enrichment profiling” (TREP), in which...

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Detalles Bibliográficos
Autores principales: Mell, Joshua Chang, Viadas, Cristina, Moleres, Javier, Sinha, Sunita, Fernández-Calvet, Ariadna, Porsch, Eric A., St. Geme, Joseph W., Nislow, Corey, Redfield, Rosemary J., Garmendia, Junkal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849778/
https://www.ncbi.nlm.nih.gov/pubmed/27124727
http://dx.doi.org/10.1371/journal.ppat.1005576