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HepatoDyn: A Dynamic Model of Hepatocyte Metabolism That Integrates (13)C Isotopomer Data
The liver performs many essential metabolic functions, which can be studied using computational models of hepatocytes. Here we present HepatoDyn, a highly detailed dynamic model of hepatocyte metabolism. HepatoDyn includes a large metabolic network, highly detailed kinetic laws, and is capable of dy...
Autores principales: | Foguet, Carles, Marin, Silvia, Selivanov, Vitaly A., Fanchon, Eric, Lee, Wai-Nang Paul, Guinovart, Joan J., de Atauri, Pedro, Cascante, Marta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849781/ https://www.ncbi.nlm.nih.gov/pubmed/27124774 http://dx.doi.org/10.1371/journal.pcbi.1004899 |
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