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Molecular analysis of a male breast cancer patient with prolonged stable disease under mTOR/PI3K inhibitors BEZ235/everolimus
The mTORC1 inhibitor everolimus (Afinitor/RAD001) has been approved for multiple cancer indications, including ER(+)/HER2(−) metastatic breast cancer. However, the combination of everolimus with the dual PI3K/mTOR inhibitor BEZ235 was shown to be more efficacious than either everolimus or BEZ235 alo...
Autores principales: | Brannon, A. Rose, Frizziero, Melissa, Chen, David, Hummel, Jennifer, Gallo, Jorge, Riester, Markus, Patel, Parul, Cheung, Wing, Morrissey, Michael, Carbone, Carmine, Cottini, Silvia, Tortora, Giampaolo, Melisi, Davide |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849849/ https://www.ncbi.nlm.nih.gov/pubmed/27148582 http://dx.doi.org/10.1101/mcs.a000620 |
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