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TRIP6 antagonizes the recruitment of A20 and CYLD to TRAF6 to promote the LPA2 receptor-mediated TRAF6 activation
The elevated lysophosphatidic acid signaling has been causally linked to cancer-associated inflammation and tumorigenesis through upregulation of nuclear factor-κB signaling. However, how this signaling event is regulated has not yet been fully understood. Here we demonstrate that TRIP6, an LPA2 rec...
Autores principales: | Lin, Fang-Tsyr, Lin, Vivian Y, Lin, Victor T G, Lin, Weei-Chin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850058/ https://www.ncbi.nlm.nih.gov/pubmed/27134758 http://dx.doi.org/10.1038/celldisc.2015.48 |
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