Atypical role of sprouty in colorectal cancer: sprouty repression inhibits epithelial–mesenchymal transition

Sprouty (SPRY) appears to act as a tumor suppressor in cancer, whereas we demonstrated that SPRY2 functions as a putative oncogene in colorectal cancer (CRC) (Oncogene, 2010, 29: 5241–5253). We investigated the mechanisms by which SPRY regulates epithelial–mesenchymal transition (EMT) in CRC. SPRY1...

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Detalles Bibliográficos
Autores principales: Zhang, Q, Wei, T, Shim, K, Wright, K, Xu, K, Palka-Hamblin, H L, Jurkevich, A, Khare, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850112/
https://www.ncbi.nlm.nih.gov/pubmed/26434583
http://dx.doi.org/10.1038/onc.2015.365

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