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Copper(II) binding properties of hepcidin

Hepcidin is a peptide hormone that regulates the homeostasis of iron metabolism. The N-terminal domain of hepcidin is conserved amongst a range of species and is capable of binding Cu(II) and Ni(II) through the amino terminal copper–nickel binding motif (ATCUN). It has been suggested that the bindin...

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Detalles Bibliográficos
Autores principales: Kulprachakarn, Kanokwan, Chen, Yu-Lin, Kong, Xiaole, Arno, Maria C., Hider, Robert C., Srichairatanakool, Somdet, Bansal, Sukhvinder S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850187/
https://www.ncbi.nlm.nih.gov/pubmed/26883683
http://dx.doi.org/10.1007/s00775-016-1342-2