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In silico transcriptional regulation and functional analysis of dengue shock syndrome associated SNPs in PLCE1 and MICB genes

Single nucleotide polymorphisms (SNPs) in PLCE1 and MICB genes increase risk for the development of dengue shock syndrome (DSS). We used Bioinformatics tools to predict alterations at the transcriptional and posttranslational levels driven by PLCE1 and MICB SNPs associated with DSS. Functional and p...

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Detalles Bibliográficos
Autores principales: Taqi, Malik Mumtaz, Waseem, Durdana, Ismatullah, Humaira, Haider, Syed Aleem, Faisal, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850189/
https://www.ncbi.nlm.nih.gov/pubmed/27038471
http://dx.doi.org/10.1007/s10142-016-0489-9

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