Sterile inflammation induced by Carbopol elicits robust adaptive immune responses in the absence of pathogen-associated molecular patterns

Carbopol is a polyanionic carbomer used in man for topical application and drug delivery purposes. However parenteral administration of Carbopol in animal models results in systemic adjuvant activity including strong pro-inflammatory type-1 T-cell (Th1) polarization. Here we investigated potential p...

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Detalles Bibliográficos
Autores principales: Gartlan, Kate H., Krashias, George, Wegmann, Frank, Hillson, William R., Scherer, Erin M., Greenberg, Philip D., Eisenbarth, Stephanie C., Moghaddam, Amin E., Sattentau, Quentin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850248/
https://www.ncbi.nlm.nih.gov/pubmed/27005810
http://dx.doi.org/10.1016/j.vaccine.2016.03.025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850248/
https://www.ncbi.nlm.nih.gov/pubmed/27005810
http://dx.doi.org/10.1016/j.vaccine.2016.03.025

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