Peptidomimetic Small Molecules Disrupt Type IV Secretion System Activity in Diverse Bacterial Pathogens

Bacteria utilize complex type IV secretion systems (T4SSs) to translocate diverse effector proteins or DNA into target cells. Despite the importance of T4SSs in bacterial pathogenesis, the mechanism by which these translocation machineries deliver cargo across the bacterial envelope remains poorly u...

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Detalles Bibliográficos
Autores principales: Shaffer, Carrie L., Good, James A. D., Kumar, Santosh, Krishnan, K. Syam, Gaddy, Jennifer A., Loh, John T., Chappell, Joseph, Almqvist, Fredrik, Cover, Timothy L., Hadjifrangiskou, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850256/
https://www.ncbi.nlm.nih.gov/pubmed/27118587
http://dx.doi.org/10.1128/mBio.00221-16

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