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Function of the Borrelia burgdorferi FtsH Homolog Is Essential for Viability both In Vitro and In Vivo and Independent of HflK/C
In many bacteria, the FtsH protease and its modulators, HflK and HflC, form a large protein complex that contributes to both membrane protein quality control and regulation of the cellular response to environmental stress. Both activities are crucial to the Lyme disease pathogen Borrelia burgdorferi...
Autores principales: | Chu, Chen-Yi, Stewart, Philip E., Bestor, Aaron, Hansen, Bryan, Lin, Tao, Gao, Lihui, Norris, Steven J., Rosa, Patricia A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850261/ https://www.ncbi.nlm.nih.gov/pubmed/27094329 http://dx.doi.org/10.1128/mBio.00404-16 |
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