PNT1 Is a C11 Cysteine Peptidase Essential for Replication of the Trypanosome Kinetoplast

The structure of a C11 peptidase PmC11 from the gut bacterium, Parabacteroides merdae, has recently been determined, enabling the identification and characterization of a C11 orthologue, PNT1, in the parasitic protozoon Trypanosoma brucei. A phylogenetic analysis identified PmC11 orthologues in bact...

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Detalles Bibliográficos
Autores principales: Grewal, Jaspreet S., McLuskey, Karen, Das, Debanu, Myburgh, Elmarie, Wilkes, Jonathan, Brown, Elaine, Lemgruber, Leandro, Gould, Matthew K., Burchmore, Richard J., Coombs, Graham H., Schnaufer, Achim, Mottram, Jeremy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850289/
https://www.ncbi.nlm.nih.gov/pubmed/26940875
http://dx.doi.org/10.1074/jbc.M116.714972

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