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Developmental Origin of Oligodendrocyte Lineage Cells Determines Response to Demyelination and Susceptibility to Age-Associated Functional Decline

Oligodendrocyte progenitors (OPs) arise from distinct ventral and dorsal domains within the ventricular germinal zones of the embryonic CNS. The functional significance, if any, of these different populations is not known. Using dual-color reporter mice to distinguish ventrally and dorsally derived...

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Detalles Bibliográficos
Autores principales: Crawford, Abbe H., Tripathi, Richa B., Richardson, William D., Franklin, Robin J.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850420/
https://www.ncbi.nlm.nih.gov/pubmed/27149850
http://dx.doi.org/10.1016/j.celrep.2016.03.069