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Evolutionary constraints over microsatellite abundance in larger mammals as a potential mechanism against carcinogenic burden

Larger organisms tend to live longer, have more potentially carcinogenic cells, and undergo more cell divisions. While one might intuitively expect cancer incidence to scale with body size, this assertion does not hold over the range of different mammals. Explaining this lack of correlation, so-call...

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Detalles Bibliográficos
Autores principales: Park, Jung Youn, An, Yong-Rock, An, Chul-Min, Kang, Jung-Ha, Kim, Eun Mi, Kim, Heebal, Cho, Seoae, Kim, Jaemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850439/
https://www.ncbi.nlm.nih.gov/pubmed/27125812
http://dx.doi.org/10.1038/srep25246